KL, klotho, 9365

N. diseases: 332; N. variants: 20
Disease: Cervix carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.040 AlteredExpression disease BEFREE Yet, the expression pattern of klotho in cervical cancer has not been determined. 26209729 2016
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.040 AlteredExpression disease BEFREE Our data demonstrated that in vivo Klotho expression was not observed in invasive cervical carcinoma. 22710352 2012
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.040 Biomarker disease BEFREE The potential anti-senescence gene Klotho (KL) has been recently found to participate in the progression of several different human cancers including breast, lung, and cervical cancer. 21523445 2011
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.040 Biomarker disease BEFREE KLOTHO mRNA was restored after treatment with either the DNA demethylating agent 2'-deoxy-5-azacytidine or histone deacetylase inhibitor trichostatin A. Methylation-specific PCR and bisulfite genomic sequencing analysis of the promoter region of KLOTHO revealed CpG hypermethylation in non-KLOTHO-expressing cervical cancer cell lines and in 41% (9/22) of invasive carcinoma cases. 20482749 2010