KL, klotho, 9365

N. diseases: 332; N. variants: 20
Disease: Metabolic Syndrome X ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.230 AlteredExpression disease BEFREE We investigated the association between serum klotho levels and MS using baseline cross-sectional data obtained from a large Korean CKD cohort. 30943913 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.230 GeneticVariation disease BEFREE In the whole population and women, the relationship between the Klotho G-395A SNP and MetS might due to its influence on high blood pressure (OR 0.48, 95% CI 0.34 to 0.67; OR 0.47, 95% CI 0.31 to 0.71, respectively) and hypertriglyceridemia (OR 0.66, 95% CI 0.39 to 0.95; OR 0.54, 95% CI 0.31 to 0.98, respectively). 26880028 2016
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.230 GeneticVariation disease BEFREE The genetic variants of Klotho might predict risk for metabolic syndrome and insulin resistance in Asian Indians. 21376714 2011
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.230 Biomarker disease RGD In vivo klotho gene delivery protects against endothelial dysfunction in multiple risk factor syndrome. 11027545 2000