NRXN3, neurexin 3, 9369

N. diseases: 64; N. variants: 29
Disease: Addictive Behavior ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085281
Disease: Addictive Behavior
Addictive Behavior 		0.040 GeneticVariation phenotype BEFREE Recent researches have implicated that mutations in the neurexin-3 (NRXN3) gene on chromosome 14q24.3-q31.1 might play a role in addiction, autism, and obesity. 23306218 2013
CUI: C0085281
Disease: Addictive Behavior
Addictive Behavior 		0.040 Biomarker phenotype BEFREE Taken together, our results confirm a role for NRXN3 in susceptibility to smoking behavior, and strongly implicate this gene in genetic vulnerability to addictive behaviors. 22716474 2012
CUI: C0085281
Disease: Addictive Behavior
Addictive Behavior 		0.040 Biomarker phenotype BEFREE The NRXN3 gene has been previously implicated in addiction and reward behavior, lending further evidence that common forms of obesity may be a central nervous system-mediated disorder. 19557197 2009
CUI: C0085281
Disease: Addictive Behavior
Addictive Behavior 		0.040 GeneticVariation phenotype BEFREE The 14q peak encompasses the NRXN3 gene (neurexin 3), which was previously identified as a potential candidate gene for addiction. 17409192 2007