|
Asthma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The expression of leptin in obese asthma group was the highest (p<0.05) ，while the expression of adiponectin the lowest (p<0.05).
|
30848574 |
2019 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
As serum adiponectin has an important function in adults for glucose and lipid metabolism, we assessed 251 participants of the Prevention and Incidence of Asthma and Mite Allergy birth cohort whether breast milk adiponectin is associated with childhood BMI and cardio-metabolic markers.
|
30728088 |
2019 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Adiponectin plays a role in asthma and obesity, but its effects and mechanism in obesity-related asthma remain elusive.
|
30584969 |
2019 |
|
Asthma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Increasing body fat in obese people leads to systemic inflammation and elevated serum levels of many proinflammatory cytokines (e.g. leptin) and anti-inflammatory ones (e.g. adiponectin) that can have a causal relationship to bronchial asthma, but human studies are ambiguous.
|
30618522 |
2018 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Body composition, asthma control, and the levels of IL-1β, -4, -13, leptin and adiponectin in obese asthmatics were significantly different from those in lean asthmatics.
|
30306746 |
2018 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
These results suggest that the IL-17-leptin/adiponectin axis plays a key role in airway inflammation in obesity-related asthma.
|
29665658 |
2018 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
However, borderline association of adiponectin with asthma was seen in adults (p=0.05), but not in children (p=0.509).
|
27473714 |
2017 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The burden of obesity in asthma and COPD: Role of adiponectin.
|
28115224 |
2017 |
|
Asthma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Serum leptin and leptin/adiponectin levels correlated positively with asthma severity and BMI (p=0.0001), but there was no correlation between adiponectin level with asthma severity and BMI (p>0.05), also serum leptin and leptin/adiponectin levels inversely correlated with FEV1 and FVC in patient (p=0.0001).
|
28411906 |
2017 |
|
Asthma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The obese subjects had higher levels of leptin and ADMA but lower levels of HMW adiponectin than the normal-weight subjects with or without asthma.
|
27337146 |
2017 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Compared with the healthy controls, patients with asthma had higher BMI (p<0.001), adiponectin (p<0.05), IL-6 (p=0.001) and CRP (p<0.001), and lower NPY levels (p<0.01).
|
27469060 |
2016 |
|
Asthma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Meanwhile, our findings suggest that ADIPOQ polymorphisms influence the risk of developing bronchial asthma in Chinese Li population.
|
26546898 |
2015 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The purpose of this study was to examine whether adiponectin might affect functions of eosinophils, which play an important role in the pathogenesis of asthma.
|
23777560 |
2013 |