Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.100 Biomarker group BEFREE Furthermore, we will elaborate on the role of adiponectin isoforms as inflammatory proteins with respect to cardiac and kidney disease and discuss the association of adiponectin with mortality. 29655459 2019
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.100 Biomarker group BEFREE Association and biomarker potential of elevated serum adiponectin with nephropathy among type 1 and type 2 diabetics: A meta-analysis. 30557306 2018
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.100 AlteredExpression group BEFREE Adiponectin expression in renal corpuscles was significantly higher in humans with known renal diseases. 29207395 2017
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.100 AlteredExpression group BEFREE Adiponectin levels in type 2 diabetics also negatively correlate with early features of nephropathy. 24417947 2014
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.100 GeneticVariation group BEFREE Adiponectin gene (ADIPOQ) polymorphisms correlate with the progression of nephropathy in Taiwanese male patients with type 2 diabetes. 24894086 2014
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.100 Biomarker group BEFREE Low levels of the adipocyte-secreted protein adiponectin correlate with albuminuria in both mice and humans, but whether adiponectin has a causative role in modulating renal disease is unknown. 23334396 2013
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.100 Biomarker group BEFREE However, although kidney disease is associated with insulin resistance, adiponectin is elevated in end-stage renal disease. 23283133 2013
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.100 GeneticVariation group BEFREE Effects of MCF2L2, ADIPOQ and SOX2 genetic polymorphisms on the development of nephropathy in type 1 Diabetes Mellitus. 20667095 2010
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.100 GeneticVariation group BEFREE The adiponectin promoter single nucleotide polymorphism (SNP) -11391G/A is found to be associated with nephropathy in type 1 diabetic (T1D) patients among Danish, but not French, Finnish, and Swedish populations. 18599322 2009
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.100 GeneticVariation group BEFREE Association of adiponectin gene polymorphisms with type 2 diabetes in an African American population enriched for nephropathy. 19056609 2009
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.100 AlteredExpression group LHGDN Serum visfatin concentration and endothelial dysfunction in chronic kidney disease. 17984105 2008
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.100 Biomarker group BEFREE To determine whether adiponectin, an adipocyte-derived hormone, is a communication signal between adipocytes and the kidney, we performed studies in a cohort of patients at high risk for diabetes and kidney disease as well as in adiponectin-knockout (Ad(-/-)) mice. 18431508 2008
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.100 Biomarker group BEFREE These findings suggest that adiponectin is a biomarker for kidney disease and may be targeted for prevention and treatment. 18431507 2008
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.100 GeneticVariation group BEFREE The T-allele of SLC2A2_16459CT was associated with a decreased risk of diabetic nephropathy (odds ratio 0.79 [95% CI 0.66-0.96], P = 0.016), whereas the T-allele of KNG_7965CT and the A-allele of ADIPOQ_prom2GA were associated with increased risk of nephropathy (1.17 [1.03-1.32], P = 0.016; 1.46 [1.11-1.93], P = 0.006, respectively). 17065357 2006
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.100 Biomarker group BEFREE Adiponectin in renal disease: relationship to phenotype and genetic variation in the gene encoding adiponectin. 14675060 2004