|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
GWASCAT |
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
|
31374203 |
2019 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
No association between common genetic variation in FOXP2 and language impairment in schizophrenia.
|
30554107 |
2019 |
|
Schizophrenia
|
0.500 |
Biomarker
|
disease |
BEFREE |
The forkhead-box P2 (<i>FOXP2</i>), involving in language and memory function, has been identified as susceptibility to schizophrenia.
|
31425145 |
2019 |
|
Schizophrenia
|
0.500 |
Biomarker
|
disease |
BEFREE |
Considering genomic alignments, TCF4 binding sites significantly overlapped those for neural DNA-binding proteins such as FOXP2 and the SCZ-associated EP300.
|
29905862 |
2018 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Thus, our results did not support the association between FOXP2 rs10447760 and schizophrenia in a Chinese Han population, and large-scale genetic replication studies with different racial and geographic origins are required in the future.
|
29346177 |
2018 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Our findings suggest that the FOXP2 rs10447760 polymorphism may not contribute to the development of schizophrenia, but may contribute to the clinical symptoms of schizophrenia among Han Chinese.
|
28421313 |
2017 |
|
Schizophrenia
|
0.500 |
Biomarker
|
disease |
PSYGENET |
Data on parental child abuse and FOXP2 SNPs previously linked to AVHs (rs1456031, rs2396753, rs2253478) were obtained from the Australian Schizophrenia Research Bank for people with schizophrenia-spectrum disorders, both with (n = 211) and without (n = 122) a lifetime history of AVHs.
|
24360035 |
2014 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Data on parental child abuse and FOXP2 SNPs previously linked to AVHs (rs1456031, rs2396753, rs2253478) were obtained from the Australian Schizophrenia Research Bank for people with schizophrenia-spectrum disorders, both with (n = 211) and without (n = 122) a lifetime history of AVHs.
|
24360035 |
2014 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Our study indicated that the rare variant rs10447760 in FoxP2 may play an important role in schizophrenia and major depression in the Chinese Han population.
|
22404659 |
2013 |
|
Schizophrenia
|
0.500 |
Biomarker
|
disease |
PSYGENET |
Our study indicated that the rare variant rs10447760 in FoxP2 may play an important role in schizophrenia and major depression in the Chinese Han population.
|
22404659 |
2013 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Here we show that the common SNP rs2396753 (C>A) gene variant of the FOXP2 gene has significant effects on GMC in patients with schizophrenia, within regions of the brain known to be affected by this disease.
|
21334420 |
2011 |
|
Schizophrenia
|
0.500 |
Biomarker
|
disease |
PSYGENET |
Our data suggest that GMC reductions in schizophrenia may be driven by C allele carriers of the FOXP2 gene variant.
|
21334420 |
2011 |
|
Schizophrenia
|
0.500 |
Biomarker
|
disease |
PSYGENET |
Twenty-seven SNPs of FOXP2 were genotyped in a cohort of 293 patients with schizophrenia and 340 controls.
|
20649982 |
2010 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Twenty-seven SNPs of FOXP2 were genotyped in a cohort of 293 patients with schizophrenia and 340 controls.
|
20649982 |
2010 |
|
Schizophrenia
|
0.500 |
Biomarker
|
disease |
BEFREE |
We screened the coding trinucleotide repeats of OTX1, EN1, DLX2, HOXA1, and FOXP2 genes in populations suffering from schizophrenia (247 patients), autism (98 patients), and idiopathic mental retardation (56 patients), and compared them with control populations (112 super controls and 202 healthy controls).
|
19018235 |
2008 |
|
Schizophrenia
|
0.500 |
AlteredExpression
|
disease |
BEFREE |
Expression of several genes associated with schizophrenia or autism including Sema3a, Trfr2 and Vldlr were found to be altered as were protein levels of Foxp2.
|
18248790 |
2008 |
|
Schizophrenia
|
0.500 |
Biomarker
|
disease |
PSYGENET |
We screened the coding trinucleotide repeats of OTX1, EN1, DLX2, HOXA1, and FOXP2 genes in populations suffering from schizophrenia (247 patients), autism (98 patients), and idiopathic mental retardation (56 patients), and compared them with control populations (112 super controls and 202 healthy controls).
|
19018235 |
2008 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
LHGDN |
Therefore, the FOXP2 gene could be considered a good candidate gene for the vulnerability to schizophrenia.
|
16538183 |
2006 |
|
Schizophrenia
|
0.500 |
Biomarker
|
disease |
BEFREE |
Therefore, the FOXP2 gene could be considered a good candidate gene for the vulnerability to schizophrenia.
|
16538183 |
2006 |
|
Schizophrenia
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
This study would not support a possible role of the two FOXP2 analyzed polymorphisms in the vulnerability to schizophrenia.
|
15653268 |
2005 |