CD28, CD28 molecule, 940

N. diseases: 364; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0747845
Disease: early pregnancy
early pregnancy
0.020 AlteredExpression phenotype BEFREE An increase in the expression of CD28 and CD86 was accompanied by a decrease in the expression of CTLA-4 in miscarriage in comparison with the early pregnancy. 21481059 2011
CUI: C0747845
Disease: early pregnancy
early pregnancy
0.020 Biomarker phenotype BEFREE The present study was undertaken to analyze the changes in the proportion of CD4(+)CD25(bright) regulatory T (Treg) cells and the expression of costimulatory molecules, CTLA-4 and CD28, in the peripheral blood and deciduas in the setting of non-pregnancy, normal early pregnancy and miscarriage. 19766059 2009