CD28, CD28 molecule, 940

N. diseases: 364; N. variants: 11
Disease: Cytokine storm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919747
Disease: Cytokine storm
Cytokine storm 		0.010 AlteredExpression disease BEFREE It is assumed widely that the drug used in this trial (TGN1412) bound to CD28 on T lymphocytes and following activation of these cells, a massive 'cytokine storm' ensued, leading ultimately to multi-organ failure in all recipients. 20964641 2010