CD28, CD28 molecule, 940

N. diseases: 364; N. variants: 11
Disease: T-lymphocyte deficiency ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1744558
Disease: T-lymphocyte deficiency
T-lymphocyte deficiency 		0.010 Biomarker disease BEFREE As upregulation of the zeta chain can also be achieved using bispecific monoclonal antibodies (BI-MoAbs) with specificity for tumor antigens and CD3 and CD28, respectively, an immunotherapy with CD3/CD30 and CD28/CD30 Bi-MoAbs may overcome and should therefore, not be jeopardized by the inherent T-cell deficiency in patients with Hodgkin's disease. 8704179 1996