RECQL5, RecQ like helicase 5, 9400

N. diseases: 28; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 Biomarker group BEFREE Collectively, our results suggested RECQL5 as a tumor suppressor in osteosarcoma and may be a potential therapeutic target for osteosarcoma treatment. 26499077 2015
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 Biomarker group BEFREE The conserved RECQ5 DNA helicase is a tumor suppressor in mammalian cells. 21402780 2011
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.030 Biomarker group BEFREE Together, our results identify RECQL5 as an important tumor suppressor that may act by preventing inappropriate HR events via Rad51 presynaptic filament disruption. 18003859 2007