NTN1, netrin 1, 9423

N. diseases: 209; N. variants: 16
Disease: Arteriosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.050 AlteredExpression disease BEFREE Netrin-1 plasma levels are lower in patients with subclinical atherosclerosis and in patients with arterial wall inflammation. 31801376 2020
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.050 Biomarker disease BEFREE Concerning the cardiovascular realm, netrin-1 promotes angiogenesis and accelerates atherosclerosis, protects the heart against ischemia-reperfusion injury, and reduces the infarct size. 24262644 2014
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.050 AlteredExpression disease BEFREE Present findings provide support for the hypothesis that dysregulation of expression of NTN1 in SMCs and its chemorepulsive receptor UNC5B in macrophages are involved in the development of atherosclerosis and unstable plaques. 24122613 2013
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.050 AlteredExpression disease BEFREE However, the mechanisms governing netrin-1 expression in atherosclerosis are not well understood. 23599441 2013
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.050 Biomarker disease BEFREE Thus, netrin-1 promoted atherosclerosis by retaining macrophages in the artery wall. 22231519 2012