NTN1, netrin 1, 9423

N. diseases: 209; N. variants: 16
Disease: Colorectal Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.040 AlteredExpression group BEFREE Expression of the netrin-1 dependence receptor UNC5C is reduced in many colorectal tumors; mice with the UNC5C mutations have increased progression of intestinal tumors. 21893118 2011
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.040 Biomarker group BEFREE We show that colorectal tumors with a gain of netrin-1 are tumors that display increased activation of the NF-kappaB pathway. 18692059 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.040 PosttranslationalModification group LHGDN Tyrosine phosphorylation of netrin receptors in netrin-1 signaling. 18253061 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.040 AlteredExpression group LHGDN Netrin induces down-regulation of its receptor, Deleted in Colorectal Cancer, through the ubiquitin-proteasome pathway in the embryonic cortical neuron. 16181408 2005