OPN4, opsin 4, 94233

N. diseases: 87; N. variants: 3
Disease: Disorder of the optic nerve ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029132
Disease: Disorder of the optic nerve
Disorder of the optic nerve 		0.020 Biomarker group BEFREE In this review, we briefly summarise the melanopsin system in the normal retina and discuss its role in connection to human aging (sleep/wake problems) and retinal pathology in Alzheimer and Parkinson diseases, diabetic retinopathy, mitochondrial optic neuropathies, glaucoma, retinitis pigmentosa, and in photophobia during migraine and in seasonal affective disorder (SAD). 31219170 2019
CUI: C0029132
Disease: Disorder of the optic nerve
Disorder of the optic nerve 		0.020 Biomarker group BEFREE Pupillometric evaluation of the melanopsin containing retinal ganglion cells in mitochondrial and non-mitochondrial optic neuropathies. 28716667 2017