GSTO1, glutathione S-transferase omega 1, 9446

N. diseases: 136; N. variants: 9
Disease: Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.340 AlteredExpression group BEFREE The increased GSTO1 expression in tumor tissue showed clear correlation with grade and stage. 28288548 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.340 Biomarker group BEFREE These potent GSTO1 inhibitors suppress cancer cell growth, enhance the cytotoxic effects of cisplatin and inhibit tumour growth in colon cancer models as single agent. 27703239 2016
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.340 Biomarker group CTD_human Potent and selective inhibitors of glutathione S-transferase omega 1 that impair cancer drug resistance. 21899313 2011
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.340 GeneticVariation group BEFREE A higher prevalence of wild-type GSTO1 (A140/A140) was significantly correlated with advanced-stage breast cancer (OR = 0.1, 95% CI, 0.01-0.77), but the presence of the genotype did not correlate with patient age at diagnosis, menopausal status, tumor size, lymph node metastasis, or estrogen-receptor status. 20210239 2010
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.340 AlteredExpression group BEFREE No or rare p28 expression was detected in normal or tumour B cells. 16639698 2006