AIM2, absent in melanoma 2, 9447

N. diseases: 165; N. variants: 1
Disease: Bacterial Infections ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		0.040 Biomarker group BEFREE To expand on these findings, we hypothesised that GLUT1-dependent glycolysis regulates acute exacerbation of lung fibrogenesis during bacterial infection via AIM2 inflammasome activation. 31822523 2020
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		0.040 Biomarker group BEFREE AIM2 senses Brucella abortus DNA in dendritic cells to induce IL-1β secretion, pyroptosis and resistance to bacterial infection in mice. 30248400 2019
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		0.040 Biomarker group BEFREE The absent in melanoma 2 (AIM2) inflammasome plays an important role in many viral and bacterial infections, but very little is known about its role in RNA virus infection, including influenza A virus (IAV). 28424239 2017
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		0.040 Biomarker group BEFREE We herein demonstrate that Absent in melanoma-2 (AIM2) contributes to the maintenance of intestinal barrier integrity and defense against bacterial infection. 26838050 2016