|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Density of CD34 positive vessels was also associated with diabetic peripheral neuropathy, independently from sex and diabetes duration [odds ratio 1.009 (95% confidence interval: 1.001-1.020), <i>p</i> = 0.037].
|
31144511 |
2019 |
|
Diabetes
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Levels of circulating CD34(+)/VEGFR2(+) and CD133(+)/VEGFR2(+) were significantly higher in the newly diagnosed untreated patients with HL compared to the patients with HL in remission (P = 0.03 and P = 0.005, respectively), in the patients in remission compared to the patients with diabetes (P = 0.011 and P < 0.001, respectively), and in the patients in remission compared to the healthy individuals (P = 0.08 and P = 0.003, respectively).
|
30549248 |
2019 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
The CD34/CD31 index was positively associated with serum triglyceride concentration (Beta: 0.26, p = 0.012) and negatively associated with serum HDL cholesterol concentration (Beta: -0.22, p = 0.027), both independently from age, sex, diabetes duration, BMI, HbA1c value, presence of hypertension, and eGFR.
|
30312628 |
2019 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
These results suggest that quantitative and functional defects of CD34+/AC133+/CD31+/CD45dim cells are associated with diabetes and vascular impairment and that this cell type may be a prognostic indicator of CVD and vascular dysfunction.
|
30321232 |
2018 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
The diabetic rats constituted the diabetes control group and a diabetes + stem cell group with local injection into the wound site of 0.5 × 106 CD34 + stem cells from human umbilical cord blood.
|
28098485 |
2017 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
To further test the significance of ATM in hematopoiesis and diabetes, we performed microarrays on circulating angiogenic cells, CD34(+) cells, obtained from a unique cohort of human subjects with long-standing (>40 years duration) poorly controlled diabetes that were free of DR. Pathway analysis of microarrays in these individuals revealed DNA repair and cell-cycle regulation as the top networks with marked upregulation of ATM mRNA compared with CD34(+) cells from diabetics with DR.
|
26502796 |
2016 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
The aim of this study was to investigate the effect of metformin on the angiogenic properties of CD34(+) cells under conditions mimicking acute myocardial infarction in diabetes.
|
26861446 |
2016 |
|
Diabetes
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Restoration of miR-92a levels in CD34(+) cells from patients with diabetes with DR reduced the inflammatory phenotype of these cells and the diabetes-induced propensity toward myeloid differentiation.
|
26283734 |
2015 |
|
Diabetes
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Notably, high-glucose treatment or diabetes reduced miR-126 levels of CD34(+) PBMCs, associated with impaired proangiogenic properties that could be rescued by miR-mimic-126 treatment.
|
23144172 |
2013 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Peripheral blood CD34(+) cells from patients with diabetes were compared with those of nondiabetic controls.
|
23230080 |
2013 |
|
Diabetes
|
0.100 |
Biomarker
|
disease |
BEFREE |
Patients with PAOD and diabetes have a higher frequency (60% vs. 45%) of advanced atherosclerotic lesions and a significant reduction (p = 0.0003) in CD34(+) capillaries in the arterial media.
|
20570185 |
2010 |