NAPSA, napsin A aspartic peptidase, 9476

N. diseases: 89; N. variants: 1
Disease: Carcinoma of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.050 Biomarker disease BEFREE We stained tissue microarrays from resected primary lung cancer (n = 665) and pulmonary metastases (n = 425) for CK7, CK20, CDX2, CK5, p40, p63, TTF-1, napsin A, GATA3, and PAX8 to systematically assess the diagnostic value of these markers. 30389437 2019
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.050 Biomarker disease BEFREE Therefore, Napsin A combined with a TKI may be a more effective treatment strategy for lung cancer. 30008942 2018
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.050 AlteredExpression disease BEFREE These data indicated that napsin A expression may inhibit TGF‑βl‑induced EMT and was negatively associated with EMT‑mediated erlotinib resistance, suggesting that napsin A expression may improve the sensitivity of lung cancer cells to EGFR‑TKI through the inhibition of EMT. 29845258 2018
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.050 AlteredExpression disease BEFREE In this study, we evaluated the expression of Napsin-A in primary pulmonary carcinoma and some cases of nonpulmonary adenocarcinoma. 22914608 2013
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.050 Biomarker disease BEFREE Pronapsin A may thus have considerable diagnostic value as a marker for primary lung cancer. 12151090 2002