|
Acinar Cell Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Whole exome sequencing reveals recurrent mutations in BRCA2 and FAT genes in acinar cell carcinomas of the pancreas.
|
25743105 |
2015 |
|
Acute Chest Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
In all patients with symptoms of ACS the amount of CD36 and MSR1 mRNA in circulating monocytes, as well as the density of both receptors on the cells surface was significantly higher.
|
22763563 |
2012 |
|
Acute Coronary Syndrome
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Highly upregulated expression of CD36 and MSR1 in circulating monocytes of patients with acute coronary syndromes.
|
22763563 |
2012 |
|
Acute lymphocytic leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
CD36-positive B-lymphoblasts Predict Poor Outcome in Children With B-lymphoblastic Leukemia.
|
28521628 |
2017 |
|
Acute monocytic leukemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Incubation with the NF-κBp50 inhibitor decreased the expression of CD36 and SIRP-α in macrophages that were treated with normal endometrial homogenate, whereas the TGF-β inhibitor enhanced the CD36 expression of THP-1 cell-derived macrophages treated with eutopic endometrial homogenate.
|
30843336 |
2019 |
|
Acute myocardial infarction
|
0.020 |
Biomarker
|
disease |
BEFREE |
Our data identify a molecular pathway of thrombosis that involves platelet MRP-14 and CD36 and suggest that targeting MRP-14 has potential for treating atherothrombotic disorders, including MI and stroke.
|
24691441 |
2014 |
|
Acute myocardial infarction
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
To determine whether either of the two platelet collagen receptor polymorphisms (GP VI T13254C and GP Ia C807T) was associated with premature acute myocardial infarction.
|
22627583 |
2012 |
|
Acute urinary tract infection
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Our study investigated the pathogenesis of <i>cnf1</i>-carrying UPEC, which affected host innate immune defenses and homeostasis through regulation of CD36 in macrophages during acute UTIs.
|
30233583 |
2018 |
|
Adenocarcinoma of pancreas
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Down-expression of CD36 in pancreatic adenocarcinoma and its correlation with clinicopathological features and prognosis.
|
29483963 |
2018 |
|
Adenoma
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Here, we discover that CD36 expression is progressively decreased from adenomas to carcinomas.
|
31484922 |
2019 |
|
Adenomatous Polyposis Coli
|
0.010 |
Biomarker
|
disease |
BEFREE |
The mouse homologue of <i>cluster of differentiation 36</i> (<i>CD36)</i> has been proposed as a modifier of disease in the MIN mouse model of FAP.
|
30065793 |
2018 |
|
Adult Acute Monocytic Leukemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Incubation with the NF-κBp50 inhibitor decreased the expression of CD36 and SIRP-α in macrophages that were treated with normal endometrial homogenate, whereas the TGF-β inhibitor enhanced the CD36 expression of THP-1 cell-derived macrophages treated with eutopic endometrial homogenate.
|
30843336 |
2019 |
|
Adult Burkitt Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Platelet surface membrane glycoproteins (GPIIb/IIIa, P-selectin and GPIV using PAC 1, CD62p and CD36 monoclonal antibodies respectively) and platelet indices (Platelet Count [PLT], Plateletcrite [PCT], Mean Platelet Volume [MPV], Platelet Distribution Width [PDW] and Platelet Large Cell Ratio [P-LCR]) were determined in children with Burkitt lymphoma and healthy children (normal controls) based on flow cytometry and automated blood cell analysis techniques.
|
31326577 |
2019 |
|
Adult Fibrosarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
HT1080 fibrosarcoma and C32 melanoma cells utilize GPIV in concert with a heparin-modulated binding systems to attach and spread on TSP.
|
1703153 |
1991 |
|
Adult Myelodysplastic Syndrome
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Overall, flow cytometry identified multiple immunophenotypic abnormalities on platelets of myelodysplastic syndrome patients, including altered light scatter characteristics, over-and under expression of specific platelet glycoproteins and asynchronous expression of CD34; decreased expression of CD36 (n = 5), CD42a (n = 1) and CD61 (n = 2), together with reactivity for CD34 (n = 1) were only observed among myelodysplastic syndrome cases, while other alterations were also found in other platelet disorders.
|
22271903 |
2012 |
|
Adult-onset citrullinemia type 2
|
0.010 |
Biomarker
|
disease |
BEFREE |
Although expression of hepatic genes associated with lipogenesis and TG hydrolysis was not changed, the mRNAs encoding enzymes/proteins involved in FA oxidation (carnitine palmitoyl-CoA transferase 1α, medium- and very-long-chain acyl-CoA dehydrogenases, and acyl-CoA oxidase 1), very-low-density lipoprotein secretion (microsomal TG transfer protein), and FA transport (CD36 and FA-binding protein 1), were markedly suppressed in CTLN2 patients.
|
25533124 |
2015 |
|
Age related macular degeneration
|
0.050 |
Biomarker
|
disease |
BEFREE |
This study supports the candidacy of CD36 as a novel susceptibility gene for neovascular AMD.
|
20157514 |
2009 |
|
Age related macular degeneration
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
Cholesterol transporters such as CD36, SR-B1 and ABCA1 gene expressions were also found to be higher (1.5, 1.9 and 2.4-fold respectively) in AMD, though not statistically significant.
|
27693409 |
2016 |
|
Age related macular degeneration
|
0.050 |
Biomarker
|
disease |
BEFREE |
CD36 gene is associated with intraocular pressure elevation after intravitreal application of anti-VEGF agents in patients with age-related macular degeneration: Implications for the safety of the therapy.
|
28557591 |
2018 |
|
Age related macular degeneration
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
Azapeptide analogues of growth hormone-releasing peptide-6 (His-d-Trp-Ala-Trp-d-Phe-Lys-NH<sub>2</sub>, GHRP-6) have for example been pursued as ligands of the cluster of differentiation 36 receptor (CD36) and show promising activity for the development of treatments for angiogenesis-related diseases, such as age-related macular degeneration, as well as for atherosclerosis.
|
28598597 |
2017 |
|
Agenesis of corpus callosum
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, EGCG dramatically increased expression of cAMP, P-PKA and P-CREBP, -AMPKα (Tr172), LKB1, P-ACC (Ser79) and lowered expression of CD36, SREBP-2, HMGCR, SREBP-1, GPAT in 1,3-DCP-treated mice livers.
|
30092300 |
2018 |
|
airway disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
These results show that CD36 and PAFR are important mediators of HDM allergy development and that inhibiting HDM engagement with PC receptors in the lung protects against allergic airway disease.
|
28667161 |
2017 |
|
Alcoholic Intoxication, Chronic
|
0.010 |
Biomarker
|
disease |
BEFREE |
For example, CDH15 and PCDH19 are associated with cognitive impairment; CDH5, CDH8, CDH9, CDH10, CDH13, CDH15, PCDH10, PCDH19 and PCDHb4 with autism; CDH7, CDH12, CDH18, PCDH12 and FAT with bipolar disease and schizophrenia; and CDH11, CDH12 and CDH13 with methamphetamine and alcohol dependency.
|
22765916 |
2012 |
|
alpha-Thalassemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We compared the prevalence of four polymorphisms, the sickle hemoglobin mutation (β globin E6V), the α-thalassemia 3.7kb deletion, glucose-6-phosphate dehydrogenase deficiency caused by the common African variant (G6PD A-), and the CD36 T188G mutation in 1344 individuals residing in districts in eastern (Tororo), south-central (Jinja), and southwestern (Kanungu) Uganda.
|
28939159 |
2017 |
|
alpha^+^ Thalassemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We compared the prevalence of four polymorphisms, the sickle hemoglobin mutation (β globin E6V), the α-thalassemia 3.7kb deletion, glucose-6-phosphate dehydrogenase deficiency caused by the common African variant (G6PD A-), and the CD36 T188G mutation in 1344 individuals residing in districts in eastern (Tororo), south-central (Jinja), and southwestern (Kanungu) Uganda.
|
28939159 |
2017 |