|
Obesity
|
0.300 |
Biomarker
|
disease |
BEFREE |
The current study tested the hypothesis that fat/fatty acid preference in obesity-prone (OP, Osborne-Mendel) and obesity-resistant (OR, S5B/Pl) rats is mediated by nutritional status and lingual CD36.
|
28302572 |
2017 |
|
Obesity
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
Taken together, this study supports the notion that CD36 - specifically rs1527483, plays a role in OFP, but not in influencing obesity in Malaysian subjects.
|
27847178 |
2017 |
|
Obesity
|
0.300 |
Biomarker
|
disease |
BEFREE |
CD36 is a scavenger and antiangiogenic receptor that is important in atherothrombotic diseases, diabetes mellitus, cancer, and obesity.
|
27013613 |
2016 |
|
Obesity
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
Here, we aimed to determine whether genetic variation in the CD36 gene affects food intake and risk of obesity.
|
28237985 |
2016 |
|
Obesity
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
We report that rs1761667 polymorphism of CD36 gene and oro-gustatory thresholds for fat might play a significant role in the development of obesity in young teenagers.
|
26556365 |
2015 |
|
Obesity
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
High affinity FA binding to CD36 and the effects of each FA on oxLDL uptake have important implications for protein conformation, binding of other ligands, functional properties of CD36, and high plasma FA levels in obesity and type 2 diabetes.
|
25555908 |
2015 |
|
Obesity
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
Human fatty acid transporter CD36 gene variations have previously been associated with fat preferences and obesity.
|
25723554 |
2015 |
|
Obesity
|
0.300 |
Biomarker
|
disease |
BEFREE |
The FAT expandability (FATe) Project: Biomarkers to determine the limit of expansion and the complications of obesity.
|
25896263 |
2015 |
|
Obesity
|
0.300 |
Biomarker
|
disease |
BEFREE |
Taken together, these studies provide novel evidence that the interaction of TSP1 with its receptor CD36 contributes to obesity--associated podocytopathy.
|
25835637 |
2015 |
|
Obesity
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
Although obesity is manifested as elevated FFA levels, the degree of EMT was not associated with the body mass index of the patients, highlighting the specific roles of CD36 and FFA uptake.
|
26424075 |
2015 |
|
Obesity
|
0.300 |
Biomarker
|
disease |
BEFREE |
The expression of pyruvate dehydrogenase kinase 4 (PDK4) and the fatty acid transporter CD36 increased in both LN and OB during HF.
|
22253914 |
2012 |
|
Obesity
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
The objective of this study was to determine whether human genetic variation in 5 common CD36 polymorphisms is associated with oral fat perception of Italian salad dressings, self-reported acceptance of high-fat foods and obesity in African-American adults (n = 317).
|
22240721 |
2012 |
|
Obesity
|
0.300 |
Biomarker
|
disease |
BEFREE |
Implication of lingual CD36 in the chemoreception of fat in foods and consequences on eating behavior and obesity risk is actively studied in various species.
|
22248592 |
2012 |
|
Obesity
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
In summary, we were unable to confirm the recently reported association of variants in CD36 with early onset obesity in populations of European ancestry.
|
20966904 |
2011 |
|
Obesity
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
Genetic variation at the CD36 loci have been associated with obesity and lipid components of the metabolic syndrome, with risk of heart disease and type 2 diabetes.
|
21250778 |
2011 |
|
Obesity
|
0.300 |
Biomarker
|
disease |
BEFREE |
Studies in rodents implicate CD36 in a number of metabolic pathways with relevance to obesity and its associated complications.
|
21912245 |
2011 |
|
Obesity
|
0.300 |
Biomarker
|
disease |
BEFREE |
To assess the relationship between CD36 gene single-nucleotide polymorphisms (SNPs) and obesity in adolescents, we evaluated the relationship between CD36 SNPs and the risk of obesity in a case-control study composed of 307 obese (age = 15.0 +/- 1.1 years) and 339 normal-weight adolescents (age = 14.6 +/- 1.1 years).
|
19893500 |
2010 |
|
Obesity
|
0.300 |
Biomarker
|
disease |
BEFREE |
To emulate the obesity phenotype in our cell culture system, we incubated cells from lean individuals with excess FA or overexpressed FAT/CD36 using recombinant adenoviral technology.
|
20427507 |
2010 |
|
Obesity
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
CD36 and SRBI mRNA were modestly altered in granulosa cells of obese compared with moderate-weight women.
|
19223519 |
2009 |
|
Obesity
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
CD36 promoter SNP allele -22674C is therefore associated with lower serum low-density lipoprotein-cholesterol in normal female twins and with improved lipid profile during weight loss and maintenance in obese subjects.
|
19016618 |
2008 |
|
Obesity
|
0.300 |
Biomarker
|
disease |
BEFREE |
FAT/CD36 gene deletion protects mice from high fat diet-induced obesity.
|
18263877 |
2008 |
|
Obesity
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
CD36 expression and its relationship with obesity in blood cells from people with and without Prader-Willi syndrome.
|
16451133 |
2006 |
|
Obesity
|
0.300 |
Biomarker
|
disease |
BEFREE |
Moreover, FATP4 and CD36 expression levels correlated with measures of obesity and insulin resistance that are influenced by both genetic and non-genetic factors (FATP4 versus BMI: r=0.53, p=0.0001; FATP4 versus body fat: r=0.51, p=0.002; FATP4 versus homeostasis model assessment [HOMA]: r=0.49, p=0.001; CD36 versus BMI: r=0.50, p=0.02; CD36 versus body fat: r=0.63, p=0.001; CD36 versus HOMA: r=0.34, p=0.06).
|
15168018 |
2004 |
|
Obesity
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
The realization that the transport step rate limits cellular fatty acid utilization suggests that abnormalities in CD36 expression or function may impact on susceptibility to certain metabolic diseases such as obesity and insulin resistance.
|
11844979 |
2002 |