CD36, CD36 molecule, 948

N. diseases: 304; N. variants: 34
Disease: Amyloidosis ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002726
Disease: Amyloidosis
Amyloidosis 		0.030 Biomarker disease BEFREE We discovered that heme and Hb suppress immune activity of primary mouse astrocytes by reducing expression of several proinflammatory cytokines (<i>e.g.</i> RANTES (regulated on activation normal T cell expressed and secreted)) and the scavenger receptor CD36 and reducing internalization of Aβ(1-42) by astrocytes. 29871926 2018
CUI: C0002726
Disease: Amyloidosis
Amyloidosis 		0.030 Biomarker disease BEFREE We have found seven molecules, structural analogues of the Trichodermamide family of natural products that interfere with the interaction CD36-amyloid β. 28150942 2017
CUI: C0002726
Disease: Amyloidosis
Amyloidosis 		0.030 AlteredExpression disease BEFREE Microglia from hypoxia-treated mice brain exhibited marked reduction in CD36 expression and inhibition of β-amyloid (Aβ) degradation. 24702189 2014