CD36, CD36 molecule, 948

N. diseases: 304; N. variants: 34
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 GeneticVariation disease BEFREE Furthermore, using a recessive inheritance model CD36 rs1761667 polymorphism was significantly associated with an increased risk of CAD with hypertension (OR = 5.677; 95% CI = 1.053-30.601; p = 0.043). 31185924 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 GeneticVariation disease BEFREE We sequenced coding regions of the cluster of differentiation 36 (CD36) gene in 184 French individuals of European ancestry presenting simultaneously with type 2 diabetes (T2D), arterial hypertension, dyslipidemia, and coronary heart disease. 31748580 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 GeneticVariation disease BEFREE Association between plasma CD36 levels and incident risk of coronary heart disease among Danish men and women. 30218892 2018
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE In conclusion, fatty acids oxidation axis PPARα-CD36-CPT1A was involved in the pro-angiogenic roles of DQP against CAD. 30564122 2018
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 AlteredExpression disease BEFREE However, recent studies challenge this conviction, showing increased incidence of coronary heart disease in the subgroup of patients with decreased expression of CD36. 28691408 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE High-density lipoprotein from subjects with coronary artery disease promotes macrophage foam cell formation: role of scavenger receptor CD36 and ERK/MAPK signaling. 27995417 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 GeneticVariation disease BEFREE Coronary arteriography and laboratory blood examinations were conducted to analyze risk factors for coronary heart disease and CD36 polymorphisms. 25299084 2014
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 GeneticVariation disease BEFREE The aim of the current study was to compare the frequency of CD36 variants in region encoding lipid-binding domain in Caucasian patients with early-onset CAD, no-CAD adult controls and neonates. 23856131 2013
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 GeneticVariation disease BEFREE The functional role of CD36 polymorphisms in CAD development needs further research. 22113854 2012
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 GeneticVariation disease BEFREE To search for associations between the CD36 gene polymorphisms and radiological markers of atherosclerosis progress in Caucasian patients with coronary artery disease (CAD) diagnosed at a young age. 22993001 2012
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 GeneticVariation disease BEFREE In humans, CD36 variants have been identified to influence free FA and high-density lipoprotein (HDL) levels and to associate with the risk of the metabolic syndrome, coronary artery disease and stroke. 20935172 2011
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 AlteredExpression disease BEFREE CD36 mRNA expression is increased in CD14+ monocytes of patients with coronary heart disease. 18067591 2008
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 GeneticVariation disease BEFREE In this study, we investigated whether genetic polymorphisms of the CD36 gene are associated with risk of coronary artery disease (CAD) in a Korean population. 17924847 2007
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 GeneticVariation disease BEFREE Our findings indicate that the A1648G polymorphism of the platelet collagen receptor plays a role in CAD in well defined patient groups. 10744142 2000
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.100 Biomarker disease BEFREE These results are the first to demonstrate that human CD36 antigen and a keratin-like protein may be additional target proteins for the anti-endothelial antibodies associated with TxCAD. 9852639 1998