CD36, CD36 molecule, 948

N. diseases: 351; N. variants: 61
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 Biomarker disease BEFREE The frequency of CD36 deficiency in northern China was low, all of them were type II deficiency, and no CD36 antibody was detected. 31421121 2019
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 Biomarker disease BEFREE Cases of CD36 deficiency are not rare in Asian populations, foetal and neonatal alloimmune thrombocytopenia (FNAIT) caused by anti-CD36 isoantibodies appears more frequent than other HPA alloantibodies. 28815406 2018
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 GeneticVariation disease BEFREE Sequencing analysis of the CD36 gene was performed to identify the mutation underlying the CD36 deficiency. 29030871 2018
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 AlteredExpression disease BEFREE In this study, we aimed to detect the expression of CD36 in two different chronic epileptic mouse models and determine whether CD36 deficiency leads to suppressive neuronal hyperexcitability and decreased susceptibility of epileptic seizures. 29111364 2017
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 CausalMutation disease CLINVAR Genetic variations of CD36 and low platelet CD36 expression - a risk factor for lipemic plasma donation in Taiwanese apheresis donors. 26528880 2016
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 Biomarker disease BEFREE We found four donors (0·6%) with type I CD36 deficiency (both platelets and monocytes CD36(null) ) and six (1·0%) with type II CD36 deficiency (PLT: CD36(null) , monocyte: CD36(low) ). 26528880 2016
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 AlteredExpression disease BEFREE A mouse tumor angiogenesis model revealed enhanced PKD-1 signaling and expression of ephrin B2 and smooth muscle actin in neovessels of Lewis Lung Carcinomas, along with low-CD36 expression or CD36 deficiency. 27013613 2016
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 GeneticVariation disease CLINVAR Incidence and molecular basis of CD36 deficiency in Shanghai population. 25330908 2015
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 AlteredExpression disease BEFREE These results demonstrated that the frequencies of Type I (lacking CD36 expression on PLTs and monocytes) and Type II (lacking CD36 expression on PLTs only) CD36 deficiency among the study population were 0.2 and 2.0%, respectively. 25330908 2015
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 CausalMutation disease CLINVAR Incidence and molecular basis of CD36 deficiency in Shanghai population. 25330908 2015
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 CausalMutation disease CLINVAR Diverse CD36 expression among Japanese population: defective CD36 mutations cause platelet and monocyte CD36 reductions in not only deficient but also normal phenotype subjects. 25798958 2015
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 GeneticVariation disease BEFREE A total of 22 variants of the CD36 gene were identified, of which five variants (111 A>T, 681 C>A, 1172-1183 del12b, 1236 delT and 1395 A>C) were novel variations, and nine were also found in single nucleotide polymorphism database (dbSNP) but had not been confirmed in individuals with CD36 deficiency. 24960640 2014
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 Biomarker disease BEFREE The role of CD36 was examined in in vitro studies and in vivo experiments, which investigated various functions of CD36 in atherosclerosis and revealed that CD36 deficiency reduces atherosclerotic lesion formation. 24903227 2014
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 GeneticVariation disease CLINVAR Studies on CD36 deficiency in South China: Two cases demonstrating the clinical impact of anti-CD36 antibodies. 23966019 2013
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 CausalMutation disease CLINVAR Studies on CD36 deficiency in South China: Two cases demonstrating the clinical impact of anti-CD36 antibodies. 23966019 2013
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 Biomarker disease BEFREE Studies on CD36 deficiency in South China: Two cases demonstrating the clinical impact of anti-CD36 antibodies. 23966019 2013
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 GeneticVariation disease BEFREE These results suggest a range of possible explanations including the existence of alternative selection pressures on CD36, co-evolution between host and parasite or confounding caused by allelic heterogeneity of CD36 deficiency. 19403559 2009
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 Biomarker disease BEFREE These results indicate that NAIT is caused by maternal CD36 deficiency having CD36 splicing abnormalities. 18462250 2008
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 Biomarker disease MGD CD36 is important for fatty acid and cholesterol uptake by the proximal but not distal intestine. 17507371 2007
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 Biomarker disease MGD CD36-facilitated fatty acid uptake inhibits leptin production and signaling in adipose tissue. 17440173 2007
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 GeneticVariation disease CLINVAR Two sibling cases of hydrops fetalis due to alloimmune anti-CD36 (Nak a) antibody. 16493488 2006
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 AlteredExpression disease BEFREE No CD36 expression in either platelets or monocytes/macrophages was shown using flow cytometer analysis and type I CD36 deficiency was diagnosed. 15912310 2005
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 AlteredExpression disease BEFREE CD36 expression and brain function: does CD36 deficiency impact learning ability? 16099393 2005
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 Biomarker disease MGD Fatty acid translocase/CD36 deficiency does not energetically or functionally compromise hearts before or after ischemia. 15023869 2004
CUI: C1842090
Disease: Platelet Glycoprotein IV Deficiency
Platelet Glycoprotein IV Deficiency 		0.900 Biomarker disease MGD Myocardial recovery from ischemia is impaired in CD36-null mice and restored by myocyte CD36 expression or medium-chain fatty acids. 12746501 2003