TBPL1, TATA-box binding protein like 1, 9519

N. diseases: 198; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.050 GeneticVariation disease BEFREE Last but not least, altered expression or activity and mutations in the TRP genes are often related to a wide range of disorders of the gut epithelium, including inflammatory bowel disease, fibrosis, visceral hyperalgesia, irritable bowel syndrome, and colorectal cancer. 31652951 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.050 Biomarker disease BEFREE Finally, we addressed the clinical relevance of our findings showing that TRF2/SULF2 expression is a worse prognostic biomarker in colorectal cancer (CRC) patients. 30698737 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.050 AlteredExpression disease BEFREE Finally, we report an inverse correlation between SIRT6 and TRF2 protein expression levels in a cohort of colon rectal cancer patients. 27923994 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.050 AlteredExpression disease BEFREE MiR-133b levels in cells and CRC tumor tissue was measured by real-time PCR.TBPL1 mRNA was detected by RT-PCR. 24870791 2014
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.050 AlteredExpression disease BEFREE The aim of this study was to determine the expression of TRF2, address the mechanism of TRF2 overexpression in human colorectal carcinoma. 19783902 2009