PTGES, prostaglandin E synthase, 9536

N. diseases: 150; N. variants: 2
Disease: Barrett Esophagus ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004763
Disease: Barrett Esophagus
Barrett Esophagus 		0.230 Biomarker disease BEFREE We found that NADPH oxidase 5 (NOX5), mPGES-1 and iNOS were significantly increased in BE mucosa. 31700071 2019
CUI: C0004763
Disease: Barrett Esophagus
Barrett Esophagus 		0.230 Biomarker disease BEFREE The prostaglandin E synthase (PGES) responsible for acid-induced PGE2 production in BE, however, is not known. 23439561 2013
CUI: C0004763
Disease: Barrett Esophagus
Barrett Esophagus 		0.230 AlteredExpression disease BEFREE Variable overexpression of PGES seems to be potentially implicated in Barrett's carcinogenesis. 18477251 2008
CUI: C0004763
Disease: Barrett Esophagus
Barrett Esophagus 		0.230 Biomarker disease RGD In the case of Barrett's oesophagus, COX-2 and mPGES-1 were predominantly in subepithelial stromal cells. mRNA levels of COX-2, mPGES-1, EP2, EP3, and EP4 were higher in the experimental groups than in controls. 14684572 2004