SOX13, SRY-box transcription factor 13, 9580

N. diseases: 17; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.100 GeneticVariation group GWASCAT A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders. 31123309 2019
Adverse effects, not elsewhere classified
0.100 GeneticVariation disease GWASCAT Genetic variation in the Estonian population: pharmacogenomics study of adverse drug effects using electronic health records. 30420678 2019
Diabetes Mellitus, Insulin-Dependent
0.050 Biomarker disease BEFREE ICA 12 antibodies were increased in either DR3 or DR4 (84% vs. 69%) positives compared to non-DR3/DR4 IDDM patients (P > 0.05). 12021135 2002
Diabetes Mellitus, Insulin-Dependent
0.050 Biomarker disease BEFREE We ascertained frequencies of autoantibodies to a suite of islet cell antigens including ICA512/IA2 and SOX13 in Asian Indians with Type 1 diabetes and in other forms of diabetes. 11323090 2001
Diabetes Mellitus, Insulin-Dependent
0.050 Biomarker disease BEFREE Linkage and association studies indicate that SOX13 is unlikely to make a substantial contribution to type 1 diabetes susceptibility. 11286511 2001
Diabetes Mellitus, Insulin-Dependent
0.050 Biomarker disease BEFREE SOX13 autoantibodies occurred at a significantly higher frequency among 188 people with type 1 diabetes (18%) than among 88 with type 2 diabetes (6%) or 175 healthy control subjects (4%). 10871192 2000
Diabetes Mellitus, Insulin-Dependent
0.050 Biomarker disease BEFREE We found SOX-13 antibodies to be present in 11 of 125 (8.8%) patients with newly diagnosed Type I diabetes and in 3 of 43 (7.0%) patients with latent autoimmune diabetes in adults. 11126406 2000
CUI: C0011847
Disease: Diabetes
Diabetes
0.030 Biomarker disease BEFREE Antibodies to new beta cell antigen ICA12 in Latvian diabetes patients. 12021128 2002
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.030 Biomarker group BEFREE Antibodies to new beta cell antigen ICA12 in Latvian diabetes patients. 12021128 2002
CUI: C0011847
Disease: Diabetes
Diabetes
0.030 Biomarker disease BEFREE We ascertained frequencies of autoantibodies to a suite of islet cell antigens including ICA512/IA2 and SOX13 in Asian Indians with Type 1 diabetes and in other forms of diabetes. 11323090 2001
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.030 Biomarker group BEFREE We ascertained frequencies of autoantibodies to a suite of islet cell antigens including ICA512/IA2 and SOX13 in Asian Indians with Type 1 diabetes and in other forms of diabetes. 11323090 2001
CUI: C0011847
Disease: Diabetes
Diabetes
0.030 AlteredExpression disease BEFREE Sex-determining region Y-related protein SOX13 is a diabetes autoantigen expressed in pancreatic islets. 10871192 2000
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus
0.030 AlteredExpression group BEFREE Sex-determining region Y-related protein SOX13 is a diabetes autoantigen expressed in pancreatic islets. 10871192 2000
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases
0.020 Biomarker group BEFREE We conclude that ICA12 represents the minor antigens in autoimmune diabetes and that, as a minor antigen, ICA12 alone does not contribute significantly in revealing new cases of autoimmunity. 12021128 2002
CUI: C0205734
Disease: Diabetes, Autoimmune
Diabetes, Autoimmune
0.020 Biomarker disease BEFREE We conclude that ICA12 represents the minor antigens in autoimmune diabetes and that, as a minor antigen, ICA12 alone does not contribute significantly in revealing new cases of autoimmunity. 12021128 2002
Latent Autoimmune Diabetes in Adults
0.020 Biomarker disease BEFREE ICA12 autoantibodies are associated with non-DR3/non-DR4 in patients with latent autoimmune diabetes in adults from northern India. 12021135 2002
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases
0.020 AlteredExpression group BEFREE Full-length SOX-13 was cloned from human brain mRNA, expressed by vitro transcription/ translation and used to detect autoantibodies by immunoprecipitation and radioligand assay in patients suffering from autoimmune diabetes or non-organ-specific autoimmune diseases. 11126406 2000
CUI: C0205734
Disease: Diabetes, Autoimmune
Diabetes, Autoimmune
0.020 Biomarker disease BEFREE Our data indicate that SOX-13 represents a minor target of autoantibodies in patients with autoimmune diabetes. 11126406 2000
Latent Autoimmune Diabetes in Adults
0.020 Biomarker disease BEFREE We found SOX-13 antibodies to be present in 11 of 125 (8.8%) patients with newly diagnosed Type I diabetes and in 3 of 43 (7.0%) patients with latent autoimmune diabetes in adults. 11126406 2000
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 Biomarker disease BEFREE Furthermore, MMP10, SOX4 and SOX13 were verified as the target genes of FOXC1 for promoting CRC metastasis. 31650548 2020
CUI: C0017638
Disease: Glioma
Glioma
0.010 Biomarker disease BEFREE Our data suggests that the feedback loop of FUS/circ_002136/miR-138-5p/SOX13 played a crucial role in the regulation of angiogenesis in glioma. 30736838 2019
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
0.010 AlteredExpression disease BEFREE It was demonstrated that miR-185 levels are significantly and inversely correlated with SOX13 levels in these NSCLC tissues, suggesting that these findings have implications for translational application with respect to NSCLC diagnostics and therapy. 30210696 2018
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.010 AlteredExpression disease BEFREE NEAT1 and SOX13 were highly expressed in MM patients and MM cell lines, and the patient survival rate and platelet count were significantly decreased in the highly expressed NEAT1 group. 30338809 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.010 Biomarker group BEFREE MiR-185 also inhibited tumor growth and suppressed SOX13 in nude mouse xenograft tumors. 30210696 2018
CUI: C4330695
Disease: Mitochondrial Diabetes
Mitochondrial Diabetes
0.010 GeneticVariation disease BEFREE The cohort was further characterized by measurement of autoantibodies to carboxypeptidase H (CPH) and SOX13 using radioligand assays, and testing for genetic mutations associated with MODY3/MODY6 and mitochondrial diabetes. 16409568 2006