CD40LG, CD40 ligand, 959

N. diseases: 393; N. variants: 9
Disease: Polymyositis ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085655
Disease: Polymyositis
Polymyositis 		0.020 AlteredExpression disease BEFREE Immunohistochemical staining revealed that CD40 was expressed on muscle cells in five of five PM and four of five DM patients, and that infiltrating mononuclear cells (MNCs) expressed CD40L in all cases of PM/DM. 10843719 2000
CUI: C0085655
Disease: Polymyositis
Polymyositis 		0.020 Biomarker disease BEFREE In an attempt to understand the mechanisms of cell injury in the inflammatory myopathies, we analyzed the expression of costimulatory molecules, CTLA4, CD28, CD86, CD40, and CD154 as well as HLA class I, HLA class II, and ICAM-I in normal muscle and in muscle biopsies from patients with polymyositis (PM) or dermatomyositis (DM). 10444360 1999