CD40LG, CD40 ligand, 959

N. diseases: 453; N. variants: 25
Disease: Carcinoma of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 Biomarker disease BEFREE DNA damage induced by human CD40 ligand mutant promotes senescence and induces demethylation of GATA4 in lung cancer. 29565449 2018
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 Biomarker disease BEFREE Incorporation of CD40 ligand enhances the immunogenicity of tumor‑associated calcium signal transducer 2 virus‑like particles against lung cancer. 29568866 2018
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 Biomarker disease BEFREE Moreover, DC-based HHP lung cancer vaccine showed functional plasticity after transfer into serum-containing media and stimulation with LPS or CD40L after additional 24h. 28187172 2017
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 Biomarker disease BEFREE These tumoricidal effects of scAAV5-CD40L-M treatment make it a promising therapeutic technique for the treatment of lung cancer. 25352298 2015
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 Biomarker disease BEFREE These results indicate that CD40L‑EXO may be used as an efficient vaccine for lung cancer immunotherapy. 24173626 2014
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 GeneticVariation disease BEFREE Anti-tumor activity of gene transfer of the membrane-stable CD40L mutant into lung cancer cells. 20811715 2010
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 Biomarker disease BEFREE To deliver the CD40L gene efficiently, we evaluated the efficiency of transduction of different serotypes of adeno-associated virus (AAV) vectors in lung cancer A549 cells and compared the transduction efficiency of a conventional AAV vector with that of self-complementary AAV (scAAV) vectors as well. 17675129 2007