SOCS5, suppressor of cytokine signaling 5, 9655

N. diseases: 38; N. variants: 5
Disease: Virus Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.010 Biomarker group BEFREE These findings indicate that gga-miR-130b-3p plays a crucial role in host defense against IBDV infection.<b>IMPORTANCE</b> This work shows that gga-miR-130b suppresses IBDV replication via directly targeting the viral genome and cellular SOCS5, the negative regulator for type I interferon expression, revealing the mechanism underlying gga-miR-130-induced inhibition of IBDV replication. 29046449 2018