CD79B, CD79b molecule, 974

N. diseases: 104; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.040 AlteredExpression disease BEFREE Furthermore, the modular DVD platform was used to prepare potent and specific ADCs targeting CD138 and CD79B, two clinically established targets overexpressed in multiple myeloma and non-Hodgkin lymphoma, respectively. 29062027 2017
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.040 AlteredExpression disease BEFREE Interestingly, we detected mRNA transcripts of CD79b in PCM cell lines, although protein translation was lacking. 21355953 2011
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.040 GeneticVariation disease LHGDN Somatic hypermutation of the B cell receptor genes B29 (Igbeta, CD79b) and mb1 (Igalpha, CD79a). 12651942 2003
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.040 Biomarker disease BEFREE Gene and protein expression (measured by flow cytometry) correlated well for CD19, CD20, CD23, and CD138 in CLL and MM, but not for immunoglobulin light chain, CD38 and CD79b in CLL, or CD45 and CD52 in MM. 12804633 2003