CD79B, CD79b molecule, 974

N. diseases: 104; N. variants: 6
Disease: B-Cell Lymphomas ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0079731
Disease: B-Cell Lymphomas
B-Cell Lymphomas 		0.040 Biomarker group BEFREE T cells redirected against Igβ for the immunotherapy of B cell lymphoma. 31624374 2020
CUI: C0079731
Disease: B-Cell Lymphomas
B-Cell Lymphomas 		0.040 Biomarker group BEFREE Our findings demonstrate that CAR T cells targeting CD79b alone or in combination have promise for treating and preventing CD19 antigen escape in B-cell lymphomas. 31439577 2019
CUI: C0079731
Disease: B-Cell Lymphomas
B-Cell Lymphomas 		0.040 GeneticVariation group LHGDN Somatic hypermutation of the B cell receptor genes B29 (Igbeta, CD79b) and mb1 (Igalpha, CD79a). 12651942 2003
CUI: C0079731
Disease: B-Cell Lymphomas
B-Cell Lymphomas 		0.040 Biomarker group BEFREE We constructed chimeric genes encoding the extracellular and transmembrane domain of human CD8 alpha and the cytoplasmic domain of Ig-alpha or Ig-beta and examined the ability of the chimeric proteins to induce signalling in the murine B-cell lymphoma A20. 7887308 1994