HDAC4, histone deacetylase 4, 9759

N. diseases: 178; N. variants: 5
Disease: Glioma ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma 		0.040 Biomarker disease BEFREE HDAC class IIa enzymes (HDAC4, 5, 7, 9) are important for glioma progression, invasion, responses to TMZ and radiotherapy, and prognosis. 30837601 2019
CUI: C0017638
Disease: Glioma
Glioma 		0.040 Biomarker disease BEFREE Interestingly, HDAC4 is highly expressed in glioma tissues, and the rate of HDAC4 nuclear import is closely correlated with glioma grade, as well as with MKK7 expression. 30963560 2019
CUI: C0017638
Disease: Glioma
Glioma 		0.040 AlteredExpression disease BEFREE Knockdown of HDAC4 substantially promoted the expression of CDK1 and CDK2 and vimentin in glioma U251 cells. 30272277 2018
CUI: C0017638
Disease: Glioma
Glioma 		0.040 AlteredExpression disease BEFREE HDAC4 expression and CIN were closely related in glioma from both functional and statistical standpoints. 25557107 2015