|
Nephropathy with Pretibial Epidermolysis Bullosa and Deafness
|
0.700 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Recessive mutation in tetraspanin CD151 causes Kindler syndrome-like epidermolysis bullosa with multi-systemic manifestations including nephropathy.
|
29138120 |
2018 |
|
Nephropathy with Pretibial Epidermolysis Bullosa and Deafness
|
0.700 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Recessive mutation in tetraspanin CD151 causes Kindler syndrome-like epidermolysis bullosa with multi-systemic manifestations including nephropathy.
|
29138120 |
2018 |
|
Nephropathy with Pretibial Epidermolysis Bullosa and Deafness
|
0.700 |
GermlineCausalMutation
|
disease |
ORPHANET |
CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin.
|
15265795 |
2004 |
|
Nephropathy with Pretibial Epidermolysis Bullosa and Deafness
|
0.700 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin.
|
15265795 |
2004 |
|
Nephropathy with Pretibial Epidermolysis Bullosa and Deafness
|
0.700 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin.
|
15265795 |
2004 |
|
Nephropathy with Pretibial Epidermolysis Bullosa and Deafness
|
0.700 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin.
|
15265795 |
2004 |
|
Nephropathy with Pretibial Epidermolysis Bullosa and Deafness
|
0.700 |
Biomarker
|
disease |
CTD_human |
|
|
|
|
Nephropathy with Pretibial Epidermolysis Bullosa and Deafness
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
|
|
|
|
Nephropathy with Pretibial Epidermolysis Bullosa and Deafness
|
0.700 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
|
|
|
|
Kidney Diseases
|
0.120 |
GeneticVariation
|
group |
BEFREE |
Recessive mutation in tetraspanin CD151 causes Kindler syndrome-like epidermolysis bullosa with multi-systemic manifestations including nephropathy.
|
29138120 |
2018 |
|
Kidney Diseases
|
0.120 |
Biomarker
|
group |
BEFREE |
Together, these results establish CD151 as a crucial modifier of integrin-mediated adhesion of podocytes to the GBM and show that blood pressure is an important factor in the initiation and progression of Cd151 knockout-induced nephropathy.
|
22201679 |
2012 |
|
Kidney Diseases
|
0.120 |
Biomarker
|
group |
HPO |
|
|
|
|
Chronic kidney disease stage 5
|
0.110 |
Biomarker
|
disease |
BEFREE |
Blood pressure influences end-stage renal disease of Cd151 knockout mice.
|
22201679 |
2012 |
|
Chronic kidney disease stage 5
|
0.110 |
Biomarker
|
disease |
HPO |
|
|
|
|
Malignant neoplasm of breast
|
0.100 |
Biomarker
|
disease |
BEFREE |
Expression of tetraspanins NET-6 and CD151 in breast cancer as a potential tumor biomarker.
|
31004251 |
2019 |
|
Malignant neoplasm of breast
|
0.100 |
Biomarker
|
disease |
BEFREE |
Here we investigated the role of CD151 in breast cancer in the context of the Wnt oncogenic activation.
|
31783316 |
2019 |
|
Malignant neoplasm of breast
|
0.100 |
Biomarker
|
disease |
BEFREE |
Analysis of tissue samples demonstrated for the first time clinical significance of CD151 in patients with ErbB2-overexpressing BCa undergone trastuzumab-based therapy.
|
30639369 |
2019 |
|
Malignant neoplasm of breast
|
0.100 |
Biomarker
|
disease |
BEFREE |
CD151 peptides as tumour vaccines triggered active anti-tumour immunity against H22 hepatoma and the lung metastasis of 4T1 breast cancer in two mouse models through the activation of CD8<sup>+</sup>IFNγ<sup>+</sup> lymphocytes and the subsequent targeted cytotoxicity.
|
31668880 |
2019 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Overall, our study suggests that CD151 is a key player in the Wnt oncogene-driven tumorigenesis and impacts breast cancer malignancy in a cell type-dependent manner.
|
31783316 |
2019 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
However, we show here that CD151 supports anti-cancer drug resistance independent of integrins.
|
30778617 |
2019 |
|
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Therefore, CD151 may serve as a potent target to regulate metastasis of clear cell sarcoma.
|
31186687 |
2019 |
|
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
CD151, a member of transmembrane 4 superfamily, has now been confirmed to be involved in tumor progression including the proliferation, migration, invasion and metastasis of tumor cells.
|
30578155 |
2019 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Expression of NET-6 and CD151 was stronger in tumors than in benign epithelial cells.
|
31004251 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In the present study, the role of CD151 in clear cell sarcoma of soft tissue was examined using a xenoplanted tumor model, which had high rates of metastasis.
|
31186687 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
CD151 peptides as tumour vaccines triggered active anti-tumour immunity against H22 hepatoma and the lung metastasis of 4T1 breast cancer in two mouse models through the activation of CD8<sup>+</sup>IFNγ<sup>+</sup> lymphocytes and the subsequent targeted cytotoxicity.
|
31668880 |
2019 |