Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE To evaluate the association between sarcopenic obesity and the decline in estimated GFR in people with type 2 diabetes. 31621107 2020
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE In American Indians with type 2 diabetes and preserved GFR at baseline, increasing ACR reflects the progression of earlier structural glomerular lesions, whereas early GFR decline may not accurately reflect such lesions. 31152118 2019
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE The aim of this study was to provide evidence for the hypothesis that estimated glomerular filtration rate from serum Cystatin C (eGFRcys) is better to be determined for all elderly type 2 diabetes mellitus (T2DM) patients based on eGFRcys upward and downward reclassification rate for hypothetical metformin dose reduction by eGFRcys at the GFR decision point of 45 mL/min/1.73 m<sup>2</sup> . 30218617 2019
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE The Error of Estimated GFR in Type 2 Diabetes Mellitus. 31561432 2019
Diabetes Mellitus, Non-Insulin-Dependent
0.100 AlteredExpression disease BEFREE Risk-scores based upon urinary proteomics did not improve prediction of renal and cardiovascular endpoints on top of standard risk factors such as age and GFR during long-term (19 years) follow up in patients with type 2-diabetes and microalbuminuria. 30282584 2018
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE ACR = albumin to creatinine ratio; BMI = body mass index; DBP = diastolic blood pressure; DM = diabetes mellitus; FBG = fasting blood glucose; GFR = glomerular filtration rate; HbA1c = hemoglobin A1c; LDL = low-density lipoprotein; SBP = systolic blood pressure; T2D = type 2 diabetes; TG = triglyceride; WC = waist circumference. 30308135 2018
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE Longitudinal Estimated GFR Trajectories in Patients With and Without Type 2 Diabetes and Nephropathy. 29153995 2018
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE Urinary albumin concentration and albumin creatinine ratio (ACR) was higher in patients with DR. ACR correlated significantly with the duration of T2DM (<i>r</i> = 0.311, <i>p</i> < 0.001), glucose (<i>r</i> = 0.479, <i>p</i> < 0.001), urea (<i>r</i> = 0.337, <i>p</i> < 0.001), creatinine (<i>r</i> = 0.275, <i>p</i> = 0.001), and GFR (<i>r</i> = -0.275, <i>p</i> < 0.001). 29176961 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker disease BEFREE An absolute, supraphysiologic elevation in GFR is observed early in the natural history in 10%-67% and 6%-73% of patients with type 1 and type 2 diabetes, respectively. 28143897 2017
Diabetes Mellitus, Non-Insulin-Dependent
0.100 AlteredExpression disease BEFREE Patients with DN score <59.5 had a significantly lower GFR level (P<0.001) and significantly older age (P<0.001), longer duration of T2DM (P<0.001) and higher risk of diabetic complications, including diabetic neuropathy (P<0.001) and peripheral vascular disease (P<0.05). 28810595 2017