MTSS1, MTSS I-BAR domain containing 1, 9788

N. diseases: 82; N. variants: 5
Disease: Leukemogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0598766
Disease: Leukemogenesis
Leukemogenesis 		0.020 Biomarker disease BEFREE Viral transduction of Mtss1 into lineage-depleted SCLtTA/Bcr-Abl bone marrow cells decreased leukemic cell burden in recipients, and leukemogenesis was reduced upon injection of Mtss1-overexpressing murine myeloid 32D cells. 26621336 2016
CUI: C0598766
Disease: Leukemogenesis
Leukemogenesis 		0.020 Biomarker disease BEFREE Thus, our data demonstrate for the first time an important role for MIM in B-cell development and suggest that predisposition of MIM-null mice to lymphomagenesis may involve aberrant interactions between B lineage cells and the lymphoid microenvironment. 22081072 2012