DisGeNET - a database of gene-disease associations

MELK, maternal embryonic leucine zipper kinase, 9833

N. diseases: 94; N. variants: 1

Disease: Mantle cell lymphoma ×

Source: ALL

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C4721414
Disease:	Mantle cell lymphoma

Mantle cell lymphoma

0.010

AlteredExpression

disease

BEFREE

MELK is highly expressed in DLBCL and MCL patient samples, correlating with a worse clinical outcome in DLBCL.

2019