CDK11B, cyclin dependent kinase 11B, 984

N. diseases: 26; N. variants: 3
Disease: Multiple malignancy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0346429
Disease: Multiple malignancy
Multiple malignancy 		0.010 Biomarker phenotype BEFREE By applying a genetic target-deconvolution strategy, we found that the mischaracterized anticancer agent OTS964 is actually a potent inhibitor of the cyclin-dependent kinase CDK11 and that multiple cancer types are addicted to CDK11 expression. 31511426 2019