MFN2, mitofusin 2, 9927

N. diseases: 334; N. variants: 75
Disease: HIV Infections ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019693
Disease: HIV Infections
HIV Infections 		0.010 AlteredExpression group BEFREE Here, we show that upon HIV infection, macrophages increase the expression of BCL2, BCLXL, TREM1, mitofusin 1 (MFN1), and MFN2 and the translocation of BCL2L11 (BIM) to the mitochondria and decrease the expression of BCL2-associated agonist of cell death (BAD) and BAX while maintaining a 95% survival rate over 28 days. 31719184 2019