KIF14, kinesin family member 14, 9928

N. diseases: 103; N. variants: 10
Disease: Liver carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.340 Biomarker disease CTD_human Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling. 28284560 2017
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.340 Biomarker disease BEFREE To the best of our knowledge, this is the first report that has identified the molecular target and oncogenic effect of KIF14 in HCC. 24854087 2014
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.340 AlteredExpression disease BEFREE We demonstrated that Sox17 is negatively related to KIF14 expression in HCC tissue and Sox17 inhibits HCC cell proliferation and migration by transcriptional downregulation of KIF14 expression. 25106407 2014
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.340 Biomarker disease BEFREE Therefore, our current study indicates that KIF14 promotes HCC carcinogenesis and may serve as a potential therapeutic target for human HCC. 23414349 2013
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.340 AlteredExpression disease BEFREE Among genes in the recurrently gained regions on 1q, expression of KIF14 and TPM3 was significantly increased, suggesting their oncogenic potential in HCC. 18803288 2008