WDR1, WD repeat domain 1, 9948

N. diseases: 59; N. variants: 41
Disease: Arteriosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.050 Biomarker disease BEFREE Approach and Results: We detected a normal AIP1 form (named AIP1A) in the healthy aorta, but a shorter form of AIP1 (named AIP1B) was found in diseased aortae that contained atherosclerotic plaques and graft arteriosclerosis. 31619063 2020
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.050 Biomarker disease BEFREE AIP1 Suppresses Transplant Arteriosclerosis Through Inhibition of Vascular Smooth Muscle Cell Inflammatory Response to IFNγ. 30471213 2019
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.050 AlteredExpression disease BEFREE <b>Objective:</b> AIP1 expression is downregulated in human atherosclerotic plaques and global deletion of AIP1 in mice exacerbates atherosclerosis in ApoE-KO mouse models. 29731721 2018
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.050 Biomarker disease BEFREE AIP1-mediated stress signaling in atherosclerosis and arteriosclerosis. 25732743 2015
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.050 Biomarker disease BEFREE AIP1 prevents graft arteriosclerosis by inhibiting interferon-γ-dependent smooth muscle cell proliferation and intimal expansion. 21700930 2011