TNFSF15, TNF superfamily member 15, 9966

N. diseases: 143; N. variants: 11
Disease: Arthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003864
Disease: Arthritis
Arthritis 		0.050 Biomarker disease BEFREE Recent findings showed elevated expression of tumor necrosis factor (TNF)-like ligand 1A (TL1A) in rheumatoid arthritis (RA) patients and arthritis mice. 30488533 2019
CUI: C0003864
Disease: Arthritis
Arthritis 		0.050 GeneticVariation disease BEFREE Besides, the genotypes of rs3810936 and rs4979462 of TNFSF15 were significantly associated with butterfly rash, arthritis, serositis, renal nephritis, hematological disorder, immunological disorder and positive antinuclear antibody (ANA) of SLE patients (all P < 0.05). 29803925 2018
CUI: C0003864
Disease: Arthritis
Arthritis 		0.050 Biomarker disease BEFREE In present study, we demonstrated that TL1A aggravated collagen-induced arthritis in mice. 19786547 2009
CUI: C0003864
Disease: Arthritis
Arthritis 		0.050 Biomarker disease LHGDN Circulating levels of TNF-like cytokine 1A (TL1A) and its decoy receptor 3 (DcR3) in rheumatoid arthritis. 18757243 2008
CUI: C0003864
Disease: Arthritis
Arthritis 		0.050 Biomarker disease BEFREE We therefore conclude that the DR3-TL1A pathway regulates joint destruction in two murine models of arthritis and represents a potential novel target for therapeutic intervention in inflammatory joint disease. 18824582 2008