TNFSF15, TNF superfamily member 15, 9966

N. diseases: 143; N. variants: 11
Disease: Graft-vs-Host Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018133
Disease: Graft-vs-Host Disease
Graft-vs-Host Disease 		0.030 Biomarker disease BEFREE Activation of the DR3-TL1A Axis in Donor Mice Leads to Regulatory T Cell Expansion and Activation With Reduction in Graft-Versus-Host Disease. 31379829 2019
CUI: C0018133
Disease: Graft-vs-Host Disease
Graft-vs-Host Disease 		0.030 Biomarker disease BEFREE Here we wanted to determine if very low doses of Tregs generated using the "2-pathway" stimulation protocol via TL1A-Ig fusion protein and low-dose IL-2 (targeting TNFRSF25 and CD25, respectively) could be used to regulate preclinical GVHD. 29751114 2018
CUI: C0018133
Disease: Graft-vs-Host Disease
Graft-vs-Host Disease 		0.030 Biomarker disease BEFREE Marked in Vivo Donor Regulatory T Cell Expansion via Interleukin-2 and TL1A-Ig Stimulation Ameliorates Graft-versus-Host Disease but Preserves Graft-versus-Leukemia in Recipients after Hematopoietic Stem Cell Transplantation. 28219835 2017