TNFSF15, TNF superfamily member 15, 9966

N. diseases: 143; N. variants: 11
Disease: Intestinal fibrosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3544347
Disease: Intestinal fibrosis
Intestinal fibrosis 		0.040 Biomarker phenotype BEFREE Recently, an important role was demonstrated for TL1A/DR3 as potential mediators of intestinal fibrosis that is associated with the presence of gut inflammation. 30972074 2019
CUI: C3544347
Disease: Intestinal fibrosis
Intestinal fibrosis 		0.040 Biomarker phenotype BEFREE Inflammation-independent TL1A-mediated intestinal fibrosis is dependent on the gut microbiome. 29988118 2018
CUI: C3544347
Disease: Intestinal fibrosis
Intestinal fibrosis 		0.040 Biomarker phenotype BEFREE TL1A blocking ameliorates intestinal fibrosis in the T cell transfer model of chronic colitis in mice. 29254800 2018
CUI: C3544347
Disease: Intestinal fibrosis
Intestinal fibrosis 		0.040 Biomarker phenotype BEFREE Our results raise the possibility for involvement of TL1A/DR3/DR3-mediated mechanisms in epithelial-mesenchymal interactions and the development of inflammation-induced intestinal fibrosis in CD. 27665176 2017