Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
0.020 Biomarker disease BEFREE In this study, FXR knockout (FXR<sup>-/-</sup>) and wild-type (WT) mice were subjected to chronic-plus-binge alcohol feeding to study the effect of FXR deficiency on ALD development. 30803859 2019
CUI: C0162309
Disease: Adrenoleukodystrophy
Adrenoleukodystrophy
0.020 Biomarker disease BEFREE Deficiency of FXR in other non-hepatic tissues and/or increased BA levels resultant from whole-body FXR deficiency might be responsible for more severe ALD development. 29730159 2018