Disease: Cholestatic liver disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0860204
Disease: Cholestatic liver disease
Cholestatic liver disease 		0.030 Biomarker disease BEFREE The combination of CVC with atRA or other FXR activators may warrant a clinical trial in patients with cholestatic liver disease. 29356312 2018
CUI: C0860204
Disease: Cholestatic liver disease
Cholestatic liver disease 		0.030 Biomarker disease BEFREE The failure of 3β-hydroxy-Δ(5)-cholenoic acids to function as FXR, PXR and CAR agonists and to exert hepatoprotective actions explains the mechanism for progressive cholestatic liver disease in patients with HSD3B7 deficiency. 24954360 2014
CUI: C0860204
Disease: Cholestatic liver disease
Cholestatic liver disease 		0.030 Biomarker disease BEFREE These functions suggest that potent PXR and FXR ligands may offer a new approach to the treatment of cholestatic liver disease. 11607932 2001