CDC42, cell division cycle 42, 998

N. diseases: 327; N. variants: 16
Disease: Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.330 GeneticVariation group BEFREE Eight tumors (including three carcinomas) had many somatic copy number variants (CNVs) with frequent deletion of CDC42 and CDKN2A, amplification of 5q31.2 and protein-altering mutations in TP53 and RB1. 24747643 2014
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.330 Biomarker group BEFREE We recently suggested that, besides their origin in the ovary, reduction of CDC42 messenger RNA (a member of the RHO GTPase family) may contribute to explain why clear cell carcinomas are not uncommonly found limited to the ovary (stage I). 21944080 2012
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.330 AlteredExpression group BEFREE In contrast, CDC42 messenger RNA levels were lower in clear cell carcinomas than high-grade serous carcinomas (P = .02). 21208644 2011
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.330 Biomarker group CTD_human Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas. 16316942 2005