CDH1, cadherin 1, 999

N. diseases: 508; N. variants: 187
Disease: Precancerous Conditions ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032927
Disease: Precancerous Conditions
Precancerous Conditions 		0.320 GeneticVariation group BEFREE This is the first study that indicates that CDH1 polymorphisms can contribute to the etiology of premalignant skin lesions in people chronically exposed to arsenic in drinking water, and that this gene may be a factor in individual susceptibility to cutaneous diseases. 22330421 2012
CUI: C0032927
Disease: Precancerous Conditions
Precancerous Conditions 		0.320 Biomarker group CTD_human Chronic aspirin use suppresses CDH1 methylation in human gastric mucosa. 19184424 2010
CUI: C0032927
Disease: Precancerous Conditions
Precancerous Conditions 		0.320 PosttranslationalModification group BEFREE Silencing of the E-cadherin gene by DNA hypermethylation around the promoter region occurs frequently, even in precancerous conditions. 12841864 2003