Breast Cancer, Familial
|
0.310 |
GeneticVariation
|
disease |
BEFREE |
Using Exome Aggregation Consortium control data, we confirm significant associations of heterozygous germ line mutations with BC for ATM (OR: 3.63, 95%CI: 2.67-4.94), CDH1 (OR: 17.04, 95%CI: 3.54-82), CHEK2 (OR: 2.93, 95%CI: 2.29-3.75), PALB2 (OR: 9.53, 95%CI: 6.25-14.51), and TP53 (OR: 7.30, 95%CI: 1.22-43.68).
|
29522266 |
2018 |
Breast Cancer, Familial
|
0.310 |
Biomarker
|
disease |
CLINGEN |
Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond.
|
26182300 |
2015 |
Breast Cancer, Familial
|
0.310 |
Biomarker
|
disease |
CLINGEN |
Germline CDH1 mutations in bilateral lobular carcinoma in situ.
|
24366306 |
2014 |
Breast Cancer, Familial
|
0.310 |
Biomarker
|
disease |
CLINGEN |
Clinical evaluation of a multiple-gene sequencing panel for hereditary cancer risk assessment.
|
24733792 |
2014 |
Breast Cancer, Familial
|
0.310 |
Biomarker
|
disease |
CLINGEN |
CDH1 germline mutations and the hereditary diffuse gastric and lobular breast cancer syndrome: a multicentre study.
|
23709761 |
2013 |
Breast Cancer, Familial
|
0.310 |
Biomarker
|
disease |
CLINGEN |
The importance of E-cadherin binding partners to evaluate the pathogenicity of E-cadherin missense mutations associated to HDGC.
|
22850631 |
2013 |
Breast Cancer, Familial
|
0.310 |
Biomarker
|
disease |
CLINGEN |
E-cadherin promotor methylation and mutation are inversely related to motility capacity of breast cancer cells.
|
23053649 |
2012 |
Breast Cancer, Familial
|
0.310 |
Biomarker
|
disease |
CLINGEN |
Germline mutations of the E-cadherin gene in families with inherited invasive lobular breast carcinoma but no diffuse gastric cancer.
|
21271559 |
2011 |
Breast Cancer, Familial
|
0.310 |
Biomarker
|
disease |
CLINGEN |
Germline E-cadherin mutations in familial lobular breast cancer.
|
17660459 |
2007 |
Breast Cancer, Familial
|
0.310 |
Biomarker
|
disease |
CLINGEN |
Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.
|
17097565 |
2006 |
Breast Cancer, Familial
|
0.310 |
Biomarker
|
disease |
CLINGEN |
Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14.
|
10074450 |
1999 |
Breast Cancer, Familial
|
0.310 |
Biomarker
|
disease |
CLINGEN |
Point mutation of the E-cadherin gene in invasive lobular carcinoma of the breast.
|
7961105 |
1994 |
Breast Cancer, Familial
|
0.310 |
Biomarker
|
disease |
CLINGEN |
E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells.
|
2007622 |
1991 |