CDH1, cadherin 1, 999

N. diseases: 73; N. variants: 158
Disease: Hereditary Nonpolyposis Colorectal Cancer ×
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1333990
Disease: Hereditary Nonpolyposis Colorectal Cancer
Hereditary Nonpolyposis Colorectal Cancer 		0.320 Biomarker disease CLINGEN Loss of CDH1 (E-cadherin) expression is associated with infiltrative tumour growth and lymph node metastasis. 26742007 2016
CUI: C1333990
Disease: Hereditary Nonpolyposis Colorectal Cancer
Hereditary Nonpolyposis Colorectal Cancer 		0.320 Biomarker disease CLINGEN Identification of seven novel germline mutations in the human E-cadherin (CDH1) gene. 17221870 2007
CUI: C1333990
Disease: Hereditary Nonpolyposis Colorectal Cancer
Hereditary Nonpolyposis Colorectal Cancer 		0.320 Biomarker disease CLINGEN Screening E-cadherin in gastric cancer families reveals germline mutations only in hereditary diffuse gastric cancer kindred. 11968083 2002
CUI: C1333990
Disease: Hereditary Nonpolyposis Colorectal Cancer
Hereditary Nonpolyposis Colorectal Cancer 		0.320 Biomarker disease CLINGEN Germline E-cadherin gene (CDH1) mutations predispose to familial gastric cancer and colorectal cancer. 10072428 1999
CUI: C1333990
Disease: Hereditary Nonpolyposis Colorectal Cancer
Hereditary Nonpolyposis Colorectal Cancer 		0.320 Biomarker disease CLINGEN Mutated epithelial cadherin is associated with increased tumorigenicity and loss of adhesion and of responsiveness to the motogenic trefoil factor 2 in colon carcinoma cells. 10051639 1999
CUI: C1333990
Disease: Hereditary Nonpolyposis Colorectal Cancer
Hereditary Nonpolyposis Colorectal Cancer 		0.320 Biomarker disease CLINGEN E-cadherin germline mutations in familial gastric cancer. 9537325 1998