ADAM10, ADAM metallopeptidase domain 10, 102

N. diseases: 224; N. variants: 27
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1194931775
rs1194931775 		1.000 0.080 15 58679139 missense variant G/A snv 4.0E-06
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		Nervous System Diseases; Mental Disorders 0.010 1.000 1 2017 2017
dbSNP: rs1336015995
rs1336015995 		1.000 0.080 15 58717640 missense variant C/T snv 8.0E-06
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		Nervous System Diseases; Mental Disorders 0.010 1.000 1 2017 2017
dbSNP: rs145518263
rs145518263 		0.925 0.080 15 58665141 missense variant T/C snv 1.7E-04 1.8E-04
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		Nervous System Diseases; Mental Disorders 0.010 1.000 1 2009 2009
dbSNP: rs2305421
rs2305421 		1.000 0.080 15 58610884 non coding transcript exon variant A/G;T snv
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		Nervous System Diseases; Mental Disorders 0.010 1.000 1 2011 2011
dbSNP: rs383902
rs383902 		1.000 0.040 15 58741975 intron variant C/T snv 0.49
CUI: C0149654
Disease: Conduct Disorder
Conduct Disorder 		Mental Disorders 0.010 1.000 1 2011 2011
dbSNP: rs514049
rs514049 		0.827 0.160 15 58750164 intron variant C/A snv 0.57
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.010 1.000 1 2018 2018
dbSNP: rs514049
rs514049 		0.827 0.160 15 58750164 intron variant C/A snv 0.57
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs514049
rs514049 		0.827 0.160 15 58750164 intron variant C/A snv 0.57
CUI: C0686619
Disease: Secondary malignant neoplasm of lymph node
Secondary malignant neoplasm of lymph node 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.010 1.000 1 2018 2018
dbSNP: rs514049
rs514049 		0.827 0.160 15 58750164 intron variant C/A snv 0.57
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma 		Neoplasms; Nervous System Diseases 0.010 1.000 1 2012 2012
dbSNP: rs514049
rs514049 		0.827 0.160 15 58750164 intron variant C/A snv 0.57
CUI: C4086165
Disease: Childhood Neuroblastoma
Childhood Neuroblastoma 		Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs61751103
rs61751103 		0.925 0.080 15 58665172 missense variant C/G snv 1.2E-03 1.5E-03
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		Nervous System Diseases; Mental Disorders 0.010 1.000 1 2009 2009
dbSNP: rs653765
rs653765 		0.763 0.240 15 58749813 upstream gene variant T/C;G snv 0.45
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.010 1.000 1 2018 2018
dbSNP: rs653765
rs653765 		0.763 0.240 15 58749813 upstream gene variant T/C;G snv 0.45
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2018 2018
dbSNP: rs653765
rs653765 		0.763 0.240 15 58749813 upstream gene variant T/C;G snv 0.45
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs653765
rs653765 		0.763 0.240 15 58749813 upstream gene variant T/C;G snv 0.45
CUI: C0686619
Disease: Secondary malignant neoplasm of lymph node
Secondary malignant neoplasm of lymph node 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.010 1.000 1 2018 2018
dbSNP: rs653765
rs653765 		0.763 0.240 15 58749813 upstream gene variant T/C;G snv 0.45
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma 		Neoplasms; Nervous System Diseases 0.010 1.000 1 2012 2012
dbSNP: rs653765
rs653765 		0.763 0.240 15 58749813 upstream gene variant T/C;G snv 0.45
CUI: C1719672
Disease: Severe Sepsis
Severe Sepsis 		Pathological Conditions, Signs and Symptoms; Infections 0.010 1.000 1 2015 2015
dbSNP: rs653765
rs653765 		0.763 0.240 15 58749813 upstream gene variant T/C;G snv 0.45
CUI: C4086165
Disease: Childhood Neuroblastoma
Childhood Neuroblastoma 		Neoplasms 0.010 1.000 1 2012 2012
dbSNP: rs653765
rs653765 		0.763 0.240 15 58749813 upstream gene variant T/C;G snv 0.45
CUI: C0243026
Disease: Sepsis
Sepsis 		Pathological Conditions, Signs and Symptoms; Infections 0.020 1.000 2 2015 2019
dbSNP: rs653765
rs653765 		0.763 0.240 15 58749813 upstream gene variant T/C;G snv 0.45
CUI: C0036690
Disease: Septicemia
Septicemia 		Pathological Conditions, Signs and Symptoms; Infections 0.020 1.000 2 2015 2019
dbSNP: rs514049
rs514049 		0.827 0.160 15 58750164 intron variant C/A snv 0.57
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		Nervous System Diseases; Mental Disorders 0.030 0.667 3 2012 2018
dbSNP: rs653765
rs653765 		0.763 0.240 15 58749813 upstream gene variant T/C;G snv 0.45
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		Nervous System Diseases; Mental Disorders 0.030 0.667 3 2012 2018
dbSNP: rs12911832
rs12911832 		1.000 0.040 15 58693705 intron variant A/T snv 0.38
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		Mental Disorders 0.700 1.000 2 2017 2019
dbSNP: rs11638416
rs11638416 		15 58598915 intron variant T/A;C snv
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 1.000 1 2012 2012
dbSNP: rs16940571
rs16940571 		15 58590593 3 prime UTR variant C/T snv 3.5E-02
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 1.000 1 2012 2012