CDKN1A, cyclin dependent kinase inhibitor 1A, 1026

N. diseases: 490; N. variants: 17
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs1059234
rs1059234 		0.790 0.120 6 36685820 3 prime UTR variant C/T snv 0.15 0.13
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.040 1.000 4 2005 2015
dbSNP: rs1059234
rs1059234 		0.790 0.120 6 36685820 3 prime UTR variant C/T snv 0.15 0.13
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.040 1.000 4 2005 2015
dbSNP: rs1059234
rs1059234 		0.790 0.120 6 36685820 3 prime UTR variant C/T snv 0.15 0.13
CUI: C1168401
Disease: Squamous cell carcinoma of the head and neck
Squamous cell carcinoma of the head and neck 		Neoplasms 0.020 1.000 2 2015 2015
dbSNP: rs1059234
rs1059234 		0.790 0.120 6 36685820 3 prime UTR variant C/T snv 0.15 0.13
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.010 1.000 1 2012 2012
dbSNP: rs1059234
rs1059234 		0.790 0.120 6 36685820 3 prime UTR variant C/T snv 0.15 0.13
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.010 < 0.001 1 2015 2015
dbSNP: rs1059234
rs1059234 		0.790 0.120 6 36685820 3 prime UTR variant C/T snv 0.15 0.13
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.010 1.000 1 2016 2016
dbSNP: rs1059234
rs1059234 		0.790 0.120 6 36685820 3 prime UTR variant C/T snv 0.15 0.13
CUI: C0007103
Disease: Malignant neoplasm of endometrium
Malignant neoplasm of endometrium 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.010 < 0.001 1 2015 2015
dbSNP: rs1059234
rs1059234 		0.790 0.120 6 36685820 3 prime UTR variant C/T snv 0.15 0.13
CUI: C0035335
Disease: Retinoblastoma
Retinoblastoma 		Neoplasms; Eye Diseases 0.010 1.000 1 2013 2013
dbSNP: rs1059234
rs1059234 		0.790 0.120 6 36685820 3 prime UTR variant C/T snv 0.15 0.13
CUI: C4048328
Disease: cervical cancer
cervical cancer 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.010 1.000 1 2012 2012
dbSNP: rs1059234
rs1059234 		0.790 0.120 6 36685820 3 prime UTR variant C/T snv 0.15 0.13
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.010 1.000 1 2012 2012
dbSNP: rs1236971182
rs1236971182 		1.000 0.080 6 36684381 missense variant C/T snv 8.1E-06
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		Neoplasms; Skin and Connective Tissue Diseases 0.010 1.000 1 1996 1996
dbSNP: rs1276639827
rs1276639827 		6 36684171 missense variant C/T snv 4.0E-06
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.010 1.000 1 2010 2010
dbSNP: rs1276639827
rs1276639827 		6 36684171 missense variant C/T snv 4.0E-06
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.010 1.000 1 2010 2010
dbSNP: rs1801270
rs1801270 		0.689 0.400 6 36684194 missense variant C/A;T snv 0.15; 4.4E-05
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		Neoplasms 0.040 1.000 4 2005 2015
dbSNP: rs1801270
rs1801270 		0.689 0.400 6 36684194 missense variant C/A;T snv 0.15; 4.4E-05
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		Neoplasms 0.040 1.000 4 2005 2015
dbSNP: rs1801270
rs1801270 		0.689 0.400 6 36684194 missense variant C/A;T snv 0.15; 4.4E-05
CUI: C0035335
Disease: Retinoblastoma
Retinoblastoma 		Neoplasms; Eye Diseases 0.030 1.000 3 2013 2018
dbSNP: rs1801270
rs1801270 		0.689 0.400 6 36684194 missense variant C/A;T snv 0.15; 4.4E-05
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.030 1.000 3 1995 2016
dbSNP: rs1801270
rs1801270 		0.689 0.400 6 36684194 missense variant C/A;T snv 0.15; 4.4E-05
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.020 0.500 2 2007 2011
dbSNP: rs1801270
rs1801270 		0.689 0.400 6 36684194 missense variant C/A;T snv 0.15; 4.4E-05
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		Neoplasms; Respiratory Tract Diseases 0.020 0.500 2 2007 2011
dbSNP: rs1801270
rs1801270 		0.689 0.400 6 36684194 missense variant C/A;T snv 0.15; 4.4E-05
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.020 0.500 2 2012 2016
dbSNP: rs1801270
rs1801270 		0.689 0.400 6 36684194 missense variant C/A;T snv 0.15; 4.4E-05
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		Neoplasms; Skin and Connective Tissue Diseases 0.020 1.000 2 1997 2006
dbSNP: rs1801270
rs1801270 		0.689 0.400 6 36684194 missense variant C/A;T snv 0.15; 4.4E-05
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		Neoplasms; Respiratory Tract Diseases 0.020 0.500 2 2007 2011
dbSNP: rs1801270
rs1801270 		0.689 0.400 6 36684194 missense variant C/A;T snv 0.15; 4.4E-05
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.020 0.500 2 2012 2016
dbSNP: rs1801270
rs1801270 		0.689 0.400 6 36684194 missense variant C/A;T snv 0.15; 4.4E-05
CUI: C4048328
Disease: cervical cancer
cervical cancer 		Neoplasms; Female Urogenital Diseases and Pregnancy Complications 0.020 0.500 2 2012 2016
dbSNP: rs1801270
rs1801270 		0.689 0.400 6 36684194 missense variant C/A;T snv 0.15; 4.4E-05
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2010 2010